Genetic engineering that aims to correct genetic defects by intervening on non-reproductive cells, a process called somatic-cell gene therapy, is in principle morally acceptable. The effects in this case are limited to a single person.

But is it not permissible to make genetic modifications that seek to transmit the effects to the subject’s offspring, called germ-line cell therapy, because of potential harm to the progeny. In the present state of research, germ-line cell therapy in all its forms is morally illicit.

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